Epidermolysis Bullosa Simplex

Epidermolysis bullosa (EB) is a rare group of inherited skin disorders that manifests as blistering of the skin in the varying degrees of severity. The severity can range from a mild, localized disease to a generalized, devastating process. The three major types of EB include simplex, junctional and dystrophic epidermolysis bullosa. EB simplex (EBS) is the most common and dominantly inherited disease. In EBS, the blisters are usually present at birth or appear during the neonatal period [1],[2]. Secondary infection is the primary complication. A newborn with extensive blistering of the skin, minimal oral lesions and secondary infection with a staphylococcus is described.