Effectiveness of zonisamide in a patient with Parkinson's disease and various levodopa-induced psychotic symptoms

被引：3
|
作者：
Yabe, Ichiro [1 ]
Ohta, Midori [2 ]
Egashira, Toshiaki [3 ]
Sato, Kazunori [1 ]
Kano, Takahiro [1 ]
Hirotani, Makoto [1 ]
Kunieda, Yasuyuki [4 ]
Sasaki, Hidenao [1 ]
机构：
[1] Hokkaido Univ, Grad Sch Med, Dept Neurol, Sapporo, Hokkaido, Japan
[2] Wakkanai City Hosp, Rehabil Ctr, Wakkanai, Hokkaido, Japan
[3] Wakkanai City Hosp, Dept Psychiat, Wakkanai, Hokkaido, Japan
[4] Wakkanai City Hosp, Dept Internal Med, Wakkanai, Hokkaido, Japan
来源：
NEUROLOGY AND CLINICAL NEUROSCIENCE | 2014年 / 2卷 / 06期
关键词：
dopamine agonists; levodopa; Parkinson's disease; psychotic symptoms; zonisamide;
D O I：
10.1111/ncn3.126
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Levodopa and dopamine agonists are useful as Parkinson's disease medications. However, they often induce persistent psychotic symptoms and motor complications, which make Parkinson's disease treatment difficult. This is a case report of a patient with advanced Parkinson's disease accompanied by exacerbation of motor symptoms and psychotic symptoms derived from prolonged use of conventional anti-Parkinson's disease drugs, and in whom adjunctive therapy with a new anti Parkinson's disease drug, zonisamide, was shown to improve motor symptoms with no exacerbation of psychotic symptoms.
引用
收藏
页码：201 / 203
页数：3
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