Effectiveness of zonisamide in a patient with Parkinson's disease and various levodopa-induced psychotic symptoms

被引：3

作者：

Yabe, Ichiro ^{[1
]}

Ohta, Midori ^{[2
]}

Egashira, Toshiaki ^{[3
]}

Sato, Kazunori ^{[1
]}

Kano, Takahiro ^{[1
]}

Hirotani, Makoto ^{[1
]}

Kunieda, Yasuyuki ^{[4
]}

Sasaki, Hidenao ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Med, Dept Neurol, Sapporo, Hokkaido, Japan

[2] Wakkanai City Hosp, Rehabil Ctr, Wakkanai, Hokkaido, Japan

[3] Wakkanai City Hosp, Dept Psychiat, Wakkanai, Hokkaido, Japan

[4] Wakkanai City Hosp, Dept Internal Med, Wakkanai, Hokkaido, Japan

来源：

NEUROLOGY AND CLINICAL NEUROSCIENCE | 2014年 / 2卷 / 06期

关键词：

dopamine agonists; levodopa; Parkinson's disease; psychotic symptoms; zonisamide;

D O I：

10.1111/ncn3.126

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Levodopa and dopamine agonists are useful as Parkinson's disease medications. However, they often induce persistent psychotic symptoms and motor complications, which make Parkinson's disease treatment difficult. This is a case report of a patient with advanced Parkinson's disease accompanied by exacerbation of motor symptoms and psychotic symptoms derived from prolonged use of conventional anti-Parkinson's disease drugs, and in whom adjunctive therapy with a new anti Parkinson's disease drug, zonisamide, was shown to improve motor symptoms with no exacerbation of psychotic symptoms.

引用

页码：201 / 203

页数：3

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