The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach

被引:17
作者
Broker, Mirelle E. E. [1 ]
Ijzermans, Jan N. M. [1 ]
van Aalten, Susanna M. [1 ]
de Man, Robert A. [2 ]
Terkivatan, Turkan [1 ]
机构
[1] Erasmus MC, Dept Surg, POB 2040, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus MC, Dept Gastroenterol & Hepatol, NL-3000 CA Rotterdam, Netherlands
关键词
D O I
10.1155/2012/725735
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Because of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it should be questioned if it is justified to discourage pregnancy in all women with HCA. The biological behavior of this benign lesion might be less threatening than presumed and a negative advice concerning pregnancy has great impact on the lives of these young female patients. The balance between the pros and cons of hepatic adenomas and pregnancy should be reconsidered. In our center, pregnancy in women with an HCA up to 5cm is no longer discouraged in close consultation with the patient, her partner, and members of the liver expert team.
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页数:3
相关论文
共 26 条
[1]   BENIGN LIVER-CELL ADENOMA ASSOCIATED WITH USE OF ORAL-CONTRACEPTIVE AGENTS [J].
BAEK, SM ;
SLOANE, CE ;
FUTTERMAN, SC .
ANNALS OF SURGERY, 1976, 183 (03) :239-242
[2]  
BAUM JK, 1973, LANCET, V2, P926
[3]   Hepatocellular Adenoma Management and Phenotypic Classification: the Bordeaux Experience [J].
Bioulac-Sage, Paulette ;
Laumonier, Herve ;
Couchy, Gabrielle ;
Le Bail, Brigitte ;
Cunha, Antonio Sa ;
Rullier, Anne ;
Laurent, Christophe ;
Blanc, Jean-Frederic ;
Cubel, Gaelle ;
Trillaud, Herve ;
Zucman-Rossi, Jessica ;
Balabaud, Charles ;
Saric, Jean .
HEPATOLOGY, 2009, 50 (02) :481-489
[4]  
Broker Mirelle E E, 2012, Ned Tijdschr Geneeskd, V156, pA5102
[5]   A review of liver masses in pregnancy and a proposed algorithm for their diagnosis and management [J].
Cobey, FC ;
Salem, RR .
AMERICAN JOURNAL OF SURGERY, 2004, 187 (02) :181-191
[6]   Liver Cell Adenoma: A Multicenter Analysis of Risk Factors for Rupture and Malignancy [J].
Deneve, Jeremiah L. ;
Pawlik, Timothy M. ;
Cunningham, Steve ;
Clary, Bryan ;
Reddy, Srinevas ;
Scoggins, Charles R. ;
Martin, Robert C. G. ;
D'Angelica, Michael ;
Staley, Charles A. ;
Choti, Michael A. ;
Jarnagin, William R. ;
Schulick, Richard D. ;
Kooby, David A. .
ANNALS OF SURGICAL ONCOLOGY, 2009, 16 (03) :640-648
[7]   A Single-Center Surgical Experience of 122 Patients With Single and Multiple Hepatocellular Adenomas [J].
Dokmak, Safi ;
Paradis, Valerie ;
Vilgrain, Valerie ;
Sauvanet, Alain ;
Farges, Olivier ;
Valla, Dominique ;
Bedossa, Pierre ;
Belghiti, Jacques .
GASTROENTEROLOGY, 2009, 137 (05) :1698-1705
[8]   Combined hepatic resection and radiofrequency ablation for multiple hepatic adenomas [J].
Fujita, Shiro ;
Kushihata, Fumiki ;
Herrmann, Glenn E. ;
Mergo, Patricia J. ;
Chen Liu ;
Nelson, David ;
Fujikawa, Takahisa ;
Hemming, Alan W. .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 (08) :1351-1354
[9]  
Kal H B, 2002, Ned Tijdschr Geneeskd, V146, P299
[10]  
KORT B, 1993, SURG GYNECOL OBSTET, V177, P371