Low resting energy expenditure in middle-aged and elderly hemodialysis patients with poor nutritional status

被引：10

作者：

Kogirima, Miho ^{[1
]}

Sakaguchi, Katsuhiko ^{[1
]}

Nishino, Kohsuke ^{[1
]}

Ichikawa, Yoko ^{[1
]}

Hiramatsu, Fumie ^{[1
]}

Yamamoto, Shigeru ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch, Inst Hlth Biosci, Dept Internal Publ Hlth Nutr, Tokushima, Japan

来源：

JOURNAL OF MEDICAL INVESTIGATION | 2006年 / 53卷 / 1-2期

关键词：

hemodialysis patient; resting energy expenditure; physical activity level; serum albumin; poor nutritional status;

D O I：

10.2152/jmi.53.34

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Due to high resting energy expenditure REE in maintenance hemodialysis patients, an increase in energy intake is usually recommended to improve their nutritional status. However, some patients appear to have poor appetite and low energy in take. In such patients low energy metabolism is expected. We hypothesized that in maintenance hemodialysis patients there are two types of the energy metabolism, high and low. This study was aimed at finding the energy metabolismin maintenance hemodialysis patients, especially in those with poor nutritional status. Subjects were hemodialysis out-patients 34 males and 20 females, mean age 59.1 center dot 10.7y center dot REE was measured by an indirect calorimeter. Protein intake was obtained from normalized protein catabolic rate nPCR, and physical activity level PAL was obtained by time study. Nutritional status assessed by serum albumin concentration was poor 3.7 center dot 0.2g/dL in spite of theadequate proteinintake 1.1 center dot 0.3g/kgperday. Only11% of the subjects had appropriate serum albumin concentration. Mean REE was 24.6 kcal/kg per day which was lower than that of healthy Japanese 26.5kcal/kg per day. REE and PAL positively correlated with serum albumin concentration p<0.01. The results suggest that maintenance hemodialysis patients with poor nutritional status may have low REE.

引用

页码：34 / 41

页数：8

共 34 条

[1]

Mehrotra R., Kopple J.D., Nutritional management of maintenance dialysis patients: Why aren't we doing better?, Annu Rev Nutr, 21, pp. 343-379, (2001)

[2]

Riella M.C., Malnutrition in dialysis: Malnourishment or uremic inflammatory response?, Kidney Int, 57, pp. 1211-1232, (2000)

[3]

Qureshi A.R., Alvestrand A., Danielsson A., Divino-Filho J.C., Gutierrez A., Lindholm B., Bergstrom J., Factors predicting malnutrition in hemodialysis patients:A cross-sectional study, Kidney Int, 53, pp. 773-782, (1998)

[4]

Ikizler T.A., Wingard R.L., Harvell J., Shyr Y., Hakim R.M., Association of morbidity with markers of nutrition and inflammation in chronic hemodialysis patients: A prospective study, Kidney Int, 55, pp. 1945-1951, (1999)

[5]

Ikizler T.A., Wingard R.L., Sun M., Harvell J., Parker R.A., Hakim R.M., Increased energy expenditure in hemodialysis patients, J Am Soc Nephrol, 7, pp. 2646-2653, (1996)

[6]

Daugirdas J.T., Second generation logarithmic estimates of single-pool variable volume Kt/V:an analysis of error, J Am Soc Nephrol, 4, pp. 1205-1213, (1993)

[7]

Shinzato T., Nakai S., Fujita Y., Takai I., Morita H., Nakane K., Maeda K., Determination of Kt/V and Protein Catabolic Rate Using Pre-and Postdialysis Blood Urea Nitrogen Concentrations, Nephron, 67, pp. 280-290, (1994)

[8]

Igawa S., Sakamaki M., Miyazaki M., Examination of the reliability of the portable calorimeter, Cli Exp Pharmacol Physiol (Suppl 29), (2002)

[9]

Kashiwazaki H., Dejima Y., Suzuki T., Influence of upper and lower thermoneutral room temperatures. (20°C and 25°C) on fasting and post-prandial resting metabolism under different outdoor temperatures, Eur J Clin Nutr, 44, pp. 405-413, (1990)

[10]

Tamura T., Ichinoseki N., Yoshimura T., Torii Y., Development and evaluation of a simple calorimeter for the measurement of resting metabolism, Clin Exp Pharmacol Physiol (Suppl 29), (2002)

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