Thermoanalytical and spectroscopic characterization of beta-cyclodextrin/ketoprofen inclusion complexes

被引：11
作者：
Marini, A
Berbenni, V
Bruni, G
Mustarelli, P
Giordano, F
Villa, M
机构：
[1] UNIV PAVIA,DIPARTIMENTO CHIM FIS,I-27100 PAVIA,ITALY
[2] CNR,CSTE,I-27100 PAVIA,ITALY
[3] UNIV PARMA,DIPARTIMENTO FARMACEUT,I-43100 PARMA,ITALY
[4] UNIV PAVIA,DIPARTIMENTO FIS GEN A VOLTA,I-27100 PAVIA,ITALY
来源：
JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY | 1995年 / 22卷 / 03期
关键词：
beta-cyclodextrin complex; ketoprofen; hydration; properties;
D O I：
10.1007/BF00707085
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method to determine the composition and hydration state of the complexes formed in aqueous solution by cyclodextrins (CD) is presented and applied to the beta-CD/ketoprofen system; it is based on a combination of spectroscopic, calorimetric, and thermogravimetric analyses. The complexes have, on average and per beta-CD mole, more than eleven water molecules, which are present in completely different bound states.
引用
收藏
页码：221 / 234
页数：14
相关论文
共 18 条
  • [1] COLTHUP NB, 1969, INTRO INFRARED RAMAN, pCH9
  • [2] FORMATION OF INCLUSION COMPLEXES OF MONODISPERSE OLIGO(ETHYLENE GLYCOL)S WITH ALPHA-CYCLODEXTRIN
    HARADA, A
    LI, J
    KAMACHI, M
    [J]. MACROMOLECULES, 1994, 27 (16) : 4538 - 4543
  • [3] THE MOLECULAR NECKLACE - A ROTAXANE CONTAINING MANY THREADED ALPHA-CYCLODEXTRINS
    HARADA, A
    LI, J
    KAMACHI, M
    [J]. NATURE, 1992, 356 (6367) : 325 - 327
  • [4] THERMODYNAMICS OF MOLECULAR RECOGNITION BY CYCLODEXTRINS .2. CALORIMETRIC TITRATION OF INCLUSION COMPLEXATION WITH MODIFIED BETA-CYCLODEXTRINS - ENTHALPY-ENTROPY COMPENSATION IN HOST-GUEST COMPLEXATION - FROM IONOPHORE TO CYCLODEXTRIN AND CYCLOPHANE
    INOUE, Y
    LIU, Y
    TONG, LH
    SHEN, BJ
    JIN, DS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (23) : 10637 - 10644
  • [5] THERMODYNAMICS OF MOLECULAR RECOGNITION BY CYCLODEXTRINS .1. CALORIMETRIC TITRATION OF INCLUSION COMPLEXATION OF NAPHTHALENESULFONATES WITH ALPHA-CYCLODEXTRIN, BETA-CYCLODEXTRIN, AND GAMMA-CYCLODEXTRIN - ENTHALPY ENTROPY COMPENSATION
    INOUE, Y
    HAKUSHI, T
    LIU, Y
    TONG, LH
    SHEN, BJ
    JIN, DS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (02) : 475 - 481
  • [6] KUROZUMI M, 1975, CHEM PHARM BULL, V23, P3062
  • [7] LI J, 1994, SCIENCE, V264, P249
  • [8] TEMPLATE-DRIVEN SELF-ASSEMBLY OF A PORPHYRIN-CONTAINING SUPRAMOLECULAR COMPLEX
    MANKA, JS
    LAWRENCE, DS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (06) : 2440 - 2442
  • [9] THERMAL STUDY OF WATER BETA-CYCLODEXTRIN INTERACTIONS
    MARINI, A
    BERBENNI, V
    MASSAROTTI, V
    MUSTARELLI, P
    RICCARDI, R
    GAZZANIGA, A
    GIORDANO, F
    BRUNI, G
    VILLA, M
    [J]. SOLID STATE IONICS, 1993, 63-5 : 358 - 362
  • [10] SELF-ASSEMBLY OF A THREADED MOLECULAR LOOP
    RAO, TVS
    LAWRENCE, DS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (09) : 3614 - 3615
12