NEURAL DARWINISM - SELECTION AND REENTRANT SIGNALING IN HIGHER BRAIN-FUNCTION

被引：353
作者：
EDELMAN, GM
机构：
[1] The Neurosciences Institute New York
来源：
NEURON | 1993年 / 10卷 / 02期
关键词：
D O I：
10.1016/0896-6273(93)90304-A
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Variation and selection within neural populations play key roles in the development and function of the brain. In this article, I review a population theory of the nervous system aimed at understanding the significance of these processes. Since its original formulation in 1978, considerable evidence has accumulated to support this theory of neuronal group selection. Extensive neural modeling based on the theory has provided useful insights into several outstanding neurobiological problems including those concerned with integration of cortical function, sensorimotor control, and perceptually based behavior.
引用
收藏
页码：115 / 125
页数：11
相关论文
共 54 条
[31]  
KOHLER W, 1947, EUR J NEUROSCI, V4, P369
[32]   INTRA-CORTICAL ARBORIZATIONS AND RECEPTIVE-FIELDS OF IDENTIFIED VENTROBASAL THALAMOCORTICAL AFFERENTS TO THE PRIMARY SOMATIC SENSORY CORTEX IN THE CAT [J].
LANDRY, P ;
DESCHENES, M .
JOURNAL OF COMPARATIVE NEUROLOGY, 1981, 199 (03) :345-371
[33]   STRUCTURAL VARIATION IN THE NERVOUS SYSTEM IN RELATION TO BEHAVIOR [J].
LASHLEY, KS .
PSYCHOLOGICAL REVIEW, 1947, 54 (06) :325-334
[34]   TOPOGRAPHIC REORGANIZATION OF SOMATOSENSORY CORTICAL AREAS 3B AND 1 IN ADULT MONKEYS FOLLOWING RESTRICTED DEAFFERENTATION [J].
MERZENICH, MM ;
KAAS, JH ;
WALL, J ;
NELSON, RJ ;
SUR, M ;
FELLEMAN, D .
NEUROSCIENCE, 1983, 8 (01) :33-55
[35]  
Michod RE, 1989, EVOLUTION, V43, P694, DOI [10.1111/j.1558-5646.1989.tb04268.x, DOI 10.1111/J.1558-5646.1989.TB04268.X]
[36]   Spatial Signaling in the Development and Function of Neural Connections [J].
Montague, P. Read ;
Gally, Joseph A. ;
Edelman, Gerald M. .
CEREBRAL CORTEX, 1991, 1 (03) :199-220
[37]   COMPETITIVE-INHIBITION OF NITRIC-OXIDE SYNTHASE PREVENTS THE CORTICAL HYPEREMIA ASSOCIATED WITH PERIPHERAL-NERVE STIMULATION [J].
NORTHINGTON, FJ ;
MATHERNE, GP ;
BERNE, RM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (14) :6649-6652
[38]   TESTS OF THE ROLES OF 2 DIFFUSIBLE SUBSTANCES IN LONG-TERM POTENTIATION - EVIDENCE FOR NITRIC-OXIDE AS A POSSIBLE EARLY RETROGRADE MESSENGER [J].
ODELL, TJ ;
HAWKINS, RD ;
KANDEL, ER ;
ARANCIO, O .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (24) :11285-11289
[39]  
PEARSON JC, 1987, J NEUROSCI, V7, P4209
[40]  
Purves D., 1988, BODY BRAIN TROPHIC T
123456