TRITERPENES OF PORIA-COCOS

被引：96
作者：
TAI, T [1 ]
AKAHORI, A [1 ]
SHINGU, T [1 ]
机构：
[1] KOBEGAKUIN UNIV,FAC PHARMACEUT SCI,NISHI KU,KOBE 65121,JAPAN
来源：
PHYTOCHEMISTRY | 1993年 / 32卷 / 05期
关键词：
PORIA-COCOS; BASIDIOMYCETES; EBURICOIC ACID; DEHYDROEBURICOIC ACID; TRAMETENOLIC ACID; 3-BETA-HYDROXYLANOSTA-7,9(11),24-TRIEN-21-OIC ACID; N-CHLOROMETHYLPHTHALIMIDE; PORICOIC ACID-C; D; PORICOIC ACID DM; AM;
D O I：
10.1016/S0031-9422(00)95099-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Four lanostane triterpenes and four novel 3,4-seco-lanostane triterpenes were isolated from the surface layer of Poria cocos. 3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid, trametenolic acid, dehydroeburicoic acid and eburicoic acid were isolated by HPLC after treatment with N-chloromethylphthalimide. Four novel 3,4-seco-lanostanes: poricoic acid C, D, DM and AM were isolated by HPLC methods. Their structures are, respectively, 3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid and 16alpha,25-dihydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid, 16alpha,25-dihydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid 3-methyl ester and 16alpha-hydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid 3-methyl ester, from spectroscopic evidence.
引用
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页码：1239 / 1244
页数：6
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