VITAMIN D AS A PROMISING ANTICANCER AGENT

被引：0

作者：

Shabana, P. ^{[1
]}

Saipriya, K. ^{[1
]}

Harini, Abbaraju Lakshmi ^{[1
]}

Sai, Pusuluri Dharani Lakshmi ^{[1
]}

Sivaiah, Konkipudi Venkata ^{[1
]}

Bonthagarala, Brahmaiah ^{[1
]}

机构：

[1] SIMS Coll Pharm, SIMS Grp Inst, Dept Pharmaceut, Guntur 522001, Andhra Pradesh, India

来源：

INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2015年 / 2卷 / 03期

关键词：

vitamin D; cancer; angiogenesis; steroid hormone;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Vitamin D is the steroid vitamin it is a group of fat soluble vitamin it helps in absorption and metabolism of calcium and phosphorous. It is a well-known essential vitamin for bone health it is mainly circulating in blood and regulating the activities of various cell types its main significances is the maintenance of plasma ca(2+) concentration. It plays a beneficial role in genesis progression and survival of cancerous growths. It mainly interferes with the various growth factors by inhibiting the proliferation of the cells angiogenesis and facilitation of the cell differentiation and apoptosis. It is not a primary anticancer agent but it poses antitumor and anti metastatic properties it may used in the treatment of cancer as a adjuvant

引用

页码：705 / 713

页数：9

共 40 条

[1]

Banwell CM, 2003, RECENT RESULTS CANC, V164, P83

[2] EXPERIMENTAL BASIS OF CANCER COMBINATION CHEMOTHERAPY WITH RETINOIDS, CYTOKINES, 1,25-DIHYDROXYVITAMIN D-3, AND ANALOGS [J].

BOLLAG, W .

JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, 56 (04) :427-435

[3]

Bouillon R, 2003, RECENT RES CANCER, V164, P353

[4] Vitamin D [J].

Brown, AJ ;

Dusso, A ;

Slatopolsky, E .

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 1999, 277 (02) :F157-F175

[5]

Byers S.W., 2011, REV ENDOCR METAB DIS

[6] Molecular basis of the selective activity of vitamin D analogues [J].

Carlberg, C .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2003, 88 (02) :274-281

[7]

Chen TC, 2003, RECENT RESULTS CANC, V164, P273

[8] Vitamin D - Molecular mechanism of action [J].

Christakos, Sylvia ;

Dhawan, Puneet ;

Benn, Bryan ;

Porta, Angela ;

Hediger, Matthias ;

Oh, Goo T. ;

Jeung, Eui-Bae ;

Zhong, Yan ;

Ajibade, Dare ;

Dhawan, Kopal ;

Joshi, Sneha .

SKELETAL BIOLOGY AND MEDICINE, PT A: ASPECTS OF BONE MORPHOGENESIS AND REMODELING, 2007, 1116 :340-348

[9] Effects of Seocalcitol (EB1089) on nitrosomethyl urea-induced rat mammary tumors [J].

Colston, KW ;

Pirianov, G ;

Bramm, E ;

Hamberg, J ;

Binderup, L .

BREAST CANCER RESEARCH AND TREATMENT, 2003, 80 (03) :303-311

[10]

Danilenko Michael, 071032824 NJ UMDNJ

← 1 2 3 4 →