INDAZOLES AS INDOLE BIOISOSTERES - SYNTHESIS AND EVALUATION OF THE TROPANYL ESTER AND AMIDE OF INDAZOLE-3-CARBOXYLATE AS ANTAGONISTS AT THE SEROTONIN 5HT3 RECEPTOR

被引：73

作者：

FLUDZINSKI, P

EVRARD, DA

BLOOMQUIST, WE

LACEFIELD, WB

PFEIFER, W

JONES, ND

DEETER, JB

COHEN, ML

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 09期

关键词：

D O I：

10.1021/jm00392a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1535 / 1537

页数：3

共 13 条

[1] THE INDAZOLE ANALOG OF SEROTONIN [J].

AINSWORTH, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (19) :5245-5247

[2] INDAZOLE ANALOG OF TRYPTAMINE - A NEW SYNTHESIS OF INDAZOLES [J].

AINSWORTH, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (19) :5242-5245

[3] PROPOSALS FOR THE CLASSIFICATION AND NOMENCLATURE OF FUNCTIONAL RECEPTORS FOR 5-HYDROXYTRYPTAMINE [J].

BRADLEY, PB ;

ENGEL, G ;

FENIUK, W ;

FOZARD, JR ;

HUMPHREY, PPA ;

MIDDLEMISS, DN ;

MYLECHARANE, EJ ;

RICHARDSON, BP ;

SAXENA, PR .

NEUROPHARMACOLOGY, 1986, 25 (06) :563-576

[4]

ELGUERO J, 1984, COMPREHENSIVE HETERO, V5, P194

[5]

FOZARD JR, 1977, BRIT J PHARMACOL, V61, pP130

[6]

FOZARD JR, 1984, MIGRAINE, P264

[7] NEUROPHARMACOLOGY - SUPER-POTENT SEROTONIN BLOCKERS [J].

IVERSEN, LL .

NATURE, 1985, 316 (6024) :107-108

[8] EFFECTS ON MIGRAINE HEADACHE OF MDL 72,222, AN ANTAGONIST AT NEURONAL 5-HT RECEPTORS - DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY [J].

LOISY, C ;

BEORCHIA, S ;

CENTONZE, V ;

FOZARD, JR ;

SCHECHTER, PJ ;

TELL, GP .

CEPHALALGIA, 1985, 5 (02) :79-82

[9] VAGAL SENSORY RECEPTORS AND THEIR REFLEX EFFECTS [J].

PAINTAL, AS .

PHYSIOLOGICAL REVIEWS, 1973, 53 (01) :159-227

[10] THE PHARMACOLOGY AND FUNCTION OF 5-HT3 RECEPTORS [J].

RICHARDSON, BP ;

ENGEL, G .

TRENDS IN NEUROSCIENCES, 1986, 9 (09) :424-428

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