Preparation, characterization, and biocompatibility of different metal oxide/PEG-based hybrid coating synthesized by sol-gel dip coating method for surface modification of titanium

被引：25

作者：

Bernedo Alcazar, Jose Carlos ^{[1
]}

Javier Lemos, Rafaela Moreira ^{[2
]}

Muniz Conde, Marcus Cristian ^{[1
]}

Chisini, Luiz Alexandre ^{[1
]}

Suca Salas, Mabel Miluska ^{[1
,3
]}

Noremberg, Bruno S. ^{[2
]}

da Motta, Fabiana Villela ^{[4
]}

Demarco, Flavio Fernando ^{[1
]}

Chaves Tarquinio, Sandra Beatriz ^{[1
]}

Villarreal Carreno, Neftali Lenin ^{[1
,2
]}

机构：

[1] Univ Fed Pelotas, Postgrad Program Dent, Pelotas, RS, Brazil

[2] Univ Fed Pelotas, Postgrad Program Sci & Mat Engn, Pelotas, RS, Brazil

[3] Univ Fed Juiz de Fora, Dept Dent, Governador Valadares, MG, Brazil

[4] Univ Fed Rio Grande do Norte, Dept Mat Engn, Ctr Technol, Natal, RN, Brazil

来源：

PROGRESS IN ORGANIC COATINGS | 2019年 / 130卷

关键词：

Sol-gel synthesis; Dip coating technique; Organic-inorganic hybrid materials; Titanium; Cell viability; IN-VITRO; IMPLANTS; INDUCTION; LITHIUM; CELLS;

D O I：

10.1016/j.porgcoat.2019.02.007

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The aim of the study was to synthesized organic-inorganic experimental nanocomposite materials via sol-gel dip coating and to characterized its biological response. The sols consist of an inorganic-organic matrix based on ZrO2, TiO2, Li+ and polyethylene glycol (PEG). The obtained hybrid-coated titanium samples have been characterized using atomic force microscope (AFM), Scanning Electronic Microscope (SEM), Energy Dispersive X-Ray Analysis (EDX). Biocompatibility of the hybrid coatings was evaluated by cytotoxicity tests. AFM analysis detailed that the obtained materials were rough nanostructured hybrids. SEM results presented covered surfaces and the presence of particles with different sizes and formats. The EDX data allowed to know the quantitative percentage of the elements present on the surface of the hybrid-coated titanium samples compatible with the sols composition. Cytotoxicity showed that all the hybrid-coated titanium samples had non-cytotoxic effect on target cells, having the groups that included Li + in the surface higher cellular grown. The sol gel dipcoating method represents a viable alternative to include inorganic and organic elements on titanium and form stable hybrid layers. The modified surfaces of titanium with the experimental materials were rough, presented biocompatible elements and allowed high cellular grown.

引用

页码：206 / 213

页数：8

共 11 条

[11] Fabrication and electrical characterization of solution-processed all-oxide transparent NiO/TiO2 p-n junction diode by sol-gel spin coating method
Cavas, M.
Gupta, R. K.
Al-Ghamdi, Ahmed. A.
Serbetci, Z.
Gafer, Zarah H.
El-Tantawy, Farid
Yakuphanoglu, F.
JOURNAL OF ELECTROCERAMICS, 2013, 31 (1-2) : 260 - 264

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