Emerging Therapeutic Options for the Management of COPD

被引：10

作者：

Reid, Debra J. ^{[1
]}

Pham, Nga T. ^{[1
]}

机构：

[1] Northeastern Univ, Sch Pharm, Dept Pharm Practice, Boston, MA 02115 USA

来源：

CLINICAL MEDICINE INSIGHTS-CIRCULATORY RESPIRATORY AND PULMONARY MEDICINE | 2013年 / 7卷

关键词：

chronic obstructive pulmonary disease; COPD therapy; long-acting muscarinic agent; phosphodiesterase-4; inhibitor; long-acting beta(2)-agonist;

D O I：

10.4137/CCRPM.S8140

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide and is projected to be the third by 2020. COPD is characterized by chronic airflow limitation caused by airway inflammation and parenchymal destruction that is usually progressive. Inhaled bronchodilators continue to be the mainstay of the current management of COPD. Safety and efficacy data of the recently approved medications including aclidinium, glycopyrronium, roflumilast, and indacaterol are reviewed here.

引用

页码：7 / 15

页数：9

共 38 条

[1]

[Anonymous], 2012, TUD PRESS ACL PACK I

[2] Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease [J].

Calverley, Peter M. A. ;

Sanchez-Torill, Fernando ;

McIvor, Andrew ;

Teichmann, Peter ;

Bredenbroeker, Dirk ;

Fabbri, Leonardo M. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 176 (02) :154-161

[3] Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials [J].

Calverley, Peter M. A. ;

Rabe, Klaus F. ;

Goehring, Udo-Michael ;

Kristiansen, Soren ;

Fabbri, Leonardo M. ;

Martinez, Fernando J. .

LANCET, 2009, 374 (9691) :685-694

[4] Lung function improvements with once-daily tiotropium in chronic obstructive pulmonary disease [J].

Casaburi, R ;

Conoscenti, CS .

AMERICAN JOURNAL OF MEDICINE, 2004, 117 :33S-40S

[5] Preclinical Evaluation of Long-Acting Muscarinic Antagonists: Comparison of Tiotropium and Investigational Drugs [J].

Casarosa, Paola ;

Bouyssou, Thierry ;

Germeyer, Sabine ;

Schnapp, Andreas ;

Gantner, Florian ;

Pieper, Michael .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009, 330 (02) :660-668

[6] Pharmacology and Therapeutics of Bronchodilators [J].

Cazzola, Mario ;

Page, Clive P. ;

Calzetta, Luigino ;

Matera, M. Gabriella .

PHARMACOLOGICAL REVIEWS, 2012, 64 (03) :450-504

[7] Efficacy and safety of once-daily NVA237 in patients with moderate-to-severe COPD: the GLOW1 trial [J].

D'Urzo, Anthony ;

Ferguson, Gary T. ;

van Noord, Jan A. ;

Hirata, Kazuto ;

Martin, Carmen ;

Horton, Rachael ;

Lu, Yimeng ;

Banerji, Donald ;

Overend, Tim .

RESPIRATORY RESEARCH, 2011, 12

[8] Chronic obstructive pulmonary disease [J].

Decramer, Marc ;

Janssens, Wim ;

Miravitlles, Marc .

LANCET, 2012, 379 (9823) :1341-1351

[9]

Donohue James F, 2005, COPD, V2, P111

[10] Once-Daily Bronchodilators for Chronic Obstructive Pulmonary Disease Indacaterol Versus Tiotropium [J].

Donohue, James F. ;

Fogarty, Charles ;

Lotvall, Jan ;

Mahler, Donald A. ;

Worth, Heinrich ;

Yorgancioglu, Arzu ;

Iqbal, Amir ;

Swales, James ;

Owen, Roger ;

Higgins, Mark ;

Kramer, Benjamin .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 182 (02) :155-162

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