THERMAL REARRANGEMENT OF ENANTIOENRICHED ALPHA-HYDROXY IMINES .1. ENANTIOCONTROLLED SYNTHESIS OF ALPHA-SUBSTITUTED ALPHA-AMINO KETONES

被引：24

作者：

COMPAIN, P ^{[1
]}

GORE, J ^{[1
]}

VATELE, JM ^{[1
]}

机构：

[1] UNIV LYON 1,CNRS,CHIM ORGAN LAB 1,F-69622 VILLEURBANNE,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 23期

关键词：

D O I：

10.1016/0040-4039(95)00680-B

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioenriched 2-allyl- and 2-(3-trimethylsilypropargyl)-2-hydroxycyclohexanone were respectively obtained by resolution from the corresponding diastereomeric acetal derived from C-2-symmetrical diol or from the camphanate ester. Study of the rearrangement of their corresponding imine derivatives has shown that it occurred with complete retention of the stereogenicity.

引用

页码：4059 / 4062

页数：4

共 20 条

[1] OXIDATION OF EPOXIDES BY DIMETHYL SULFOXIDE - A SIMPLE SYNTHESIS OF ALPHA-HYDROXY KETONES [J].