Myasthenia gravis as interdisciplinary disease based on a case report

Background. Myasthenia gravis (MG) is the most common primary disorder of the neuromuscular junction, caused by autoantibodies to the muscle acetylocholine receptors, blocking the acetylocholine binding site and provoking accelerated receptor degradation; complement destroys the post-synaptic membrane. In time in postsynaptic membrane reaches to structural changes, resulting in chronic weakness of muscles. Etiology of myasthenia gravis is not still known despite research. Peak incidence falls in women between twenty and thirty years of age, and in men between fifty and sixty years of age. Case report. We described therapeutic methods for patients with myasthenia gravis based on case report of a patient with recurrent neoplasm - thymoma. Conclusions. Only complex and multidisciplinary approach is essential in the management of complicated MG cases.