DEVELOPMENT OF NEW ANALYTICAL METHODS FOR QUANTITATIVE ESTIMATION OF RACECADOTRIL AS AN ACTIVE PHARMACEUTICAL INGREDIEN BY UV SPECTROPHOTOMETER

A simple and sensitive spectroscopic method was developed for the estimation of Racecadotril in pharmaceutical dosage forms. This method is based on Racecadotril, showing absorbance at 231 nm in methanol. This method obeys Beers law in the concentration range of 8 to 100 mu g mL(-1) respectively. The proposed method is precise, accurate and reproducible and can be extended to the analysis of Racecadotril in bulk and tablet formulations. The method was linear (r=0.9998) at concentrations ranging from 8 to 100 mu g ml(-1), precise (repeatability and intermediated precision), exact (method of standard addition), and Limit of detection mu g ml(-1) (0.088749). Limit of quantification mu g ml(-1) (0.268938) was found and the % recovery is found 99.69%.