PREMENSTRUAL TENSION - A PLACEBO-CONTROLLED EFFICACY STUDY WITH SPIRONOLACTONE AND MEDROXYPROGESTERONE ACETATE

被引：29
作者：
HELLBERG, D
CLAESSON, B
NILSSON, S
机构：
[1] Department of Obstetrics and Gynecology, Falu Hospital, Falun
来源：
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1991年 / 34卷 / 03期
关键词：
PREMENSTRUAL TENSION; TREATMENT; SPIRONOLACTONE; MEDROXYPROGESTERONE ACETATE;
D O I：
10.1016/0020-7292(91)90357-B
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Forty-three healthy women with a characteristic history of premenstrual tension participated in a placebo controlled, crossover study. The effects of spironolactone (Aldactone) and medroxyprogesterone acetate (Gestapuran) on ten symptoms of premenstrual tension were evaluated. Placebo tablets as well as spironolactone and medroxyprogesterone acetate significantly improved a mood index score (which ia a generally accepted method to measure premenstrual symptoms). Spironolactone and medroxyprogesterone acetate were however both significantly (P < 0.05) better than placebo in relieving the symptoms.
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收藏
页码：243 / 248
页数：6
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