Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy

被引：2
|
作者：
Fujimura, Taku [1 ]
Tanita, Kayo [1 ]
Sato, Yota [1 ]
Kambayashi, Yumi [1 ]
Furudate, Sadanori [1 ]
Tsukada, Akira [1 ]
Hashimoto, Akira [1 ]
Aiba, Setsuya [1 ]
机构：
[1] Tohoku Univ, Grad Sch Med, Dept Dermatol, Sendai, Miyagi, Japan
来源：
CASE REPORTS IN ONCOLOGY | 2018年 / 11卷 / 01期
关键词：
Erythrodermic mycosis fungoides; Mogamulizumab; Etoposide;
D O I：
10.1159/000486278
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Mogamulizumab induces cytotoxicity against CCR4+ lymphoma cells by antibody-dependent cell-mediated cytotoxicity in advanced cutaneous T-cell lymphoma patients. Since the efficacy of mogamulizumab in mycosis fungoides (28.6%) is lower than that in Sezary syndrome (47.1%), reagents that enhance the antitumor immune response induced by mogamulizumab are needed to further optimize its use for the treatment of erythrodermic mycosis fungoides. In this report, we present a case of erythrodermic mycosis fungoides successfully treated with mogamulizumab followed by etoposide monotherapy. (C) 2018 The Author(s) Published by S. Karger AG, Basel
引用
收藏
页码：29 / 32
页数：4
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