Advances in the adjuvant and neoadjuvant treatment of breast cancer

被引:1
作者
Briest, Susanne [1 ,2 ]
Stearns, Vered [2 ]
机构
[1] Univ Leipzig, Dept Gynecol & Obstet, Leipzig, Germany
[2] Johns Hopkins Sch Med, Sidney Kimmel Comprehens Canc Ctr, 1650 Orleans St,CRB 1,Room 1M-53, Baltimore, MD 21231 USA
关键词
adjuvant treatment; aromatase inhibitors; breast cancer; chemotherapy; hormonal therapy; neoadjuvant treatment; trastuzumab;
D O I
10.2217/17455057.3.3.325
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Several advances in the adjuvant systemic therapy of primary breast cancer have occurred in the last decade and contributed to a decline in disease-related mortality. These include the introduction of aromatase inhibitors, new chemotherapy agents, and the novel antibody trastuzumab. New supportive treatments, such as growth factors, have contributed to the optimization of chemotherapy dose and schedule, and have improved the efficacy and safety of the treatment. In this review we will outline some of the recent advances in the adjuvant and neoadjuvant treatment of breast cancer. We will also discuss ongoing and proposed clinical trials.
引用
收藏
页码:325 / 339
页数:15
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