RESISTANCE TO THE POLYETHER IONOPHORE ANTIBIOTIC PANDAVIR (NIGERICIN) IN 2 PRODUCING STRAINS OF STREPTOMYCES

被引：1
作者：
MONCHEVA, PA [1 ]
CHRISTOVA, KR [1 ]
IVANOVA, IV [1 ]
机构：
[1] UNIV SOFIA,DEPT MICROBIOL,BU-1000 SOFIA,BULGARIA
来源：
JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 08期
关键词：
D O I：
10.7164/antibiotics.48.811
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In two pandavir (nigericin) producing strains, Streptomyces hygroscopicus 155 and Streptomyces albogriseolus 444, an enzyme activity was detected leading to inactivation of the antibiotic in the presence of ATP-Na-2. Apparently, the observed inactivation is specific for the antibiotic produced by these strains. The nigericin producing strains were also found to be less permeable to pandavir than their non-producing variants.
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页码：811 / 814
页数：4
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