PROTECTIVE EFFECTS OF HEALON AND OCCUCOAT AGAINST AIR BUBBLE ENDOTHELIAL DAMAGE DURING ULTRASONIC AGITATION OF THE ANTERIOR-CHAMBER

被引：0

作者：

MONSON, MC ^{[1
]}

TAMURA, M ^{[1
]}

MAMALIS, N ^{[1
]}

OLSON, RJ ^{[1
]}

机构：

[1] UNIV UTAH,SCH MED,INTERMT OCULAR RES CTR,SALT LAKE CITY,UT 84112

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1991年 / 17卷 / 05期

关键词：

AIR BUBBLE; ANTERIOR CHAMBER AGITATION; CHONDROITIN SULFATE; CORNEAL ENDOTHELIUM; HYDROXYPROPYLMETHYLCELLULOSE; SODIUM HYALURONATE;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

An important aspect of any new viscoelastic substance is the corneal endothelial protection. We compared the protective effects of sodium hyaluronate (Healon(R)) and hydroxypropylmethylcellulose (Occucoat(R)) by introducing a controlled volume of air bubbles into the anterior chamber of human eye bank eyes during ultrasonic agitation, of the anterior chamber. Eight eyes received Healon and 11 eyes received Occucoat. Damage to endothelial cells in the central cornea was quantified by vital staining. Endothelial damage averaged 4.5% in eyes in which no viscoelastic was used (positive control); damage was 0.4% in eyes in which a viscoelastic was injected but no air bubbles were introduced (negative control). We found that endothelial damage averaged 4.25% in specimens that received air plus Healon and 1.4% in specimens that received air plus Occucoat. Occucoat appeared to have somewhat better protective effects than Healon against air bubble damage to the corneal endothelium during ultrasonic agitation of the anterior chamber.

引用

页码：613 / 616

页数：4