EFFECTS OF TREATMENT WITH SIMVASTATIN AND PRAVASTATIN ON COGNITIVE FUNCTION IN PATIENTS WITH HYPERCHOLESTEROLEMIA

被引：41
|
作者：
CUTLER, N
SRAMEK, J
VEROFF, A
BLOCK, G
STAUFFER, L
LINES, C
机构：
[1] CALIF CLIN TRIALS,BEVERLY HILLS,CA 90211
[2] MERCK SHARP & DOHME LTD,RES LABS,BLUE BELL,PA 19422
来源：
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1995年 / 39卷 / 03期
关键词：
SIMVASTATIN; PRAVASTATIN; CHOLESTEROL; COGNITIVE FUNCTION;
D O I：
10.1111/j.1365-2125.1995.tb04458.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The effects of equi-efficacious doses of the cholesterol-lowering drugs simvastatin (20 mg day(-1)) and pravastatin (40 mg day(-1)) on tests of cognitive function were investigated in a double-blind, placebo-controlled, 2-period (4 weeks per period), incomplete block, crossover study of 36 patients (24 per treatment) with hypercholesterolaemia. After 4 weeks neither of the active treatments differed significantly from placebo on any cognitive measure.
引用
收藏
页码：333 / 336
页数：4
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