FORMATION OF ISOINDOLINE DERIVATIVES FROM O-BROMOACETYLBENZOPHENONES

被引：11

作者：

NANYA, S

ISHIDA, H

BUTSUGAN, Y

机构：

[1] Department of Applied Chemistry, Nagoya Institute of Technology, Nagoya, 466, Gokiso, Showa‐ku

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1994年 / 31卷 / 06期

关键词：

D O I：

10.1002/jhet.5570310677

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

o-Dibromoacetylbenzophenone, 2 or o-bromoacetylbenzophenone 3 reacted with aqueous ammonia to produce 3-phenylisoindolin-1-one 5. The reaction of 3 with methylamine afforded 3-hydroxy-2-methyl-3-phenyl-isoindolin-1-one 4 and 2-methyl-3-phenylisoindolin-1-one 5. Whereas from 2 with methylamine only 5 was obtained.

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页码：1725 / 1726

页数：2

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