FORMATION OF ISOINDOLINE DERIVATIVES FROM O-BROMOACETYLBENZOPHENONES

被引：11
作者：
NANYA, S
ISHIDA, H
BUTSUGAN, Y
机构：
[1] Department of Applied Chemistry, Nagoya Institute of Technology, Nagoya, 466, Gokiso, Showa‐ku
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1994年 / 31卷 / 06期
关键词：
D O I：
10.1002/jhet.5570310677
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
o-Dibromoacetylbenzophenone, 2 or o-bromoacetylbenzophenone 3 reacted with aqueous ammonia to produce 3-phenylisoindolin-1-one 5. The reaction of 3 with methylamine afforded 3-hydroxy-2-methyl-3-phenyl-isoindolin-1-one 4 and 2-methyl-3-phenylisoindolin-1-one 5. Whereas from 2 with methylamine only 5 was obtained.
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页码：1725 / 1726
页数：2
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