THE EFFECT OF 6-KHZ TONE EXPOSURE ON INNER-EAR FUNCTION OF THE GUINEA-PIG - RELATION TO CHANGES IN COCHLEAR MICROPHONICS, ACTION-POTENTIAL, ENDOCOCHLEAR POTENTIAL AND CHEMICAL-POTENTIALS OF K+-IONS AND NA+-IONS, USING A DOUBLE-BARREL GLASS-ELECTRODE

被引:0
|
作者
SUGISAWA, T [1 ]
ISHIDA, A [1 ]
HOTTA, S [1 ]
YAMAMURA, K [1 ]
机构
[1] ASAHIKAWA MED COLL,DEPT HYG,4-5-3-11 NISHIKAGURA,ASAHIKAWA 078,JAPAN
关键词
NOISE EXPOSURE; 6 KHZ SOUND; INNER EAR FUNCTION; COCHLEAR MICROPHONICS; NERVE ACTION POTENTIAL;
D O I
暂无
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Using 97 male albino guinea pigs and applying electrophysiological methods, the effects of a 6 kHz tone were investigated at a moderate sound pressure level to the inner ear during a 24-h exposure time. Following exposure to the 6 kHz tone at 90 dB, cochleas showed decreased maximum output voltage of cochlear microphonics (CM) and action potential (AP). In the endolymph, K+ ion and Na+ ion concentrations remained unchanged during 40 min anoxia and 90 dB tone exposure. At 80 dB sound exposure decreases in maximum output voltage of CM and AP and decreases in the absolute value of EP could not be detected. Endolymph K+-ion Na+-ion concentrations were also unchanged. These findings indicate that diffusion potentials are induced at the same time as decreases of maximum output voltage in CM induced by exposure to sound at 90 dB.
引用
收藏
页码:154 / 159
页数:6
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