INHIBITION OF CYTOCHROME-P-450 ACTIVITY IN RAT-LIVER MICROSOMES BY THE NATURALLY-OCCURRING FLAVONOID, QUERCETIN

被引：101

作者：

SOUSA, RL ^{[1
]}

MARLETTA, MA ^{[1
]}

机构：

[1] MIT,DEPT APPL BIOL SCI,ROOM 56 229,CAMBRIDGE,MA 02139

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1985年 / 240卷 / 01期

关键词：

D O I：

10.1016/0003-9861(85)90040-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：345 / 357

页数：13

共 33 条

[1]

BUENING MK, 1981, CANCER RES, V41, P67

[2]

BUENING MK, 1974, MOL PHARMACOL, V10, P999

[3]

BURKE MD, 1974, DRUG METAB DISPOS, V2, P583

[4]

COOPER TG, 1977, TOOLS BIOCH, P32

[5] PHENOTYPING OF CYTOCHROMES-P-450 IN HUMAN-TISSUES WITH MONOCLONAL-ANTIBODIES [J].

FUJINO, T ;

PARK, SS ;

WEST, D ;

GELBOIN, HV .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (12) :3682-3686

[6] EFFECT OF DRUG SUBSTRATES ON REDUCTION OF HEPATIC MICROSOMAL CYTOCHROME P-450 BY NADPH [J].

GIGON, PL ;

GRAM, TE ;

GILLETTE, JR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 31 (04) :558-&

[7] PURIFICATION AND CHARACTERIZATION OF LIVER MICROSOMAL CYTOCHROMES-P-450 - ELECTROPHORETIC, SPECTRAL, CATALYTIC, AND IMMUNOCHEMICAL PROPERTIES AND INDUCIBILITY OF 8 ISOZYMES ISOLATED FROM RATS TREATED WITH PHENOBARBITAL OR BETA-NAPHTHOFLAVONE [J].

GUENGERICH, FP ;

DANNAN, GA ;

WRIGHT, ST ;

MARTIN, MV ;

KAMINSKY, LS .

BIOCHEMISTRY, 1982, 21 (23) :6019-6030

[8]

HAUGEN DA, 1976, J BIOL CHEM, V251, P1817

[9]

Herrmann K., 1976, Journal of Food Technology, V11, P433, DOI 10.1108/09566160010378107

[10]

Hildebrandt A G, 1978, Methods Enzymol, V52, P342

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