LACK OF EFFECT OF ATENOLOL AND NADOLOL ON THE METABOLISM OF THEOPHYLLINE

被引:6
作者
CORSI, CM
NAFZIGER, AN
PIEPER, JA
BERTINO, JS
机构
[1] MARY IMOGENE BASSETT HOSP,PHARM SERV,COOPERSTOWN,NY 13326
[2] MARY IMOGENE BASSETT HOSP,MED SERV,COOPERSTOWN,NY 13326
[3] UNIV COLORADO,SCH PHARM,DENVER,CO 80202
关键词
D O I
10.1111/j.1365-2125.1990.tb03632.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The effects of 7 days of pretreatment with atenolol, 150 mg day‐1, or nadolol, 80 mg day‐1, on the pharmacokinetics and metabolism of theophylline were determined in six male smokers. Theophylline clearance, volume of distribution, half‐life and the urinary excretion of theophylline and its metabolites were unchanged during either treatment compared with control. 1990 The British Pharmacological Society
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页码:265 / 268
页数:4
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