Substantial radiation reduction in pediatric and adult congenital heart disease interventions with a novel X-ray imaging technology

Background: Pediatric catheterization exposes patients to varying radiation doses. Concerns over the effects of X-ray radiation dose on the patient population have increased in recent years. This study aims at quantifying the patient radiation dose reduction after the introduction of an X-ray imaging technology using advanced real time image noise reduction algorithms and optimized acquisition chain for fluoroscopy and exposure in a pediatric and adult population with congenital heart disease. Methods: Patient and radiation dose data was retrospectively collected (July 2012-February 2013) for 338 consecutive patients treated with a system using state of the art image processing and reference acquisition chain (referred as "reference system"). The same data was collected (March-October 2013) for 329 consecutive patients treated with the new imaging technology (Philips AlluraClarity, referred as "new system"). Patients were divided into three weight groups: A) below 10 kg, B) 10-40 kg, and C) over 40 kg. Radiation dose was quantified using dose area product (DAP), while procedure complexity using fluoroscopy time, procedure duration and volume of contrast medium. Results: The new system provides significant patient dose reduction compared to the reference system. Median DAP values were reduced in group A) from 140.6 cGy.cm(2) to 60.7 cGy.cm(2), in group B) from 700.0 cGy.cm(2) to 202.2 cGy.cm(2) and in group C) from 4490.4 cGy.cm(2) to 1979.8 cGy.cm(2) with reduction of 57%, 71% and 56% respectively (p < 0.0001 for all groups). Conclusions: Despite no other changes in procedural approach, the novel X-ray imaging technology provided substantial radiation dose reduction of 56% or higher. (C) 2015 The Authors. Published by Elsevier Ireland Ltd.