PET AND FUNCTIONAL TESTING IN TEMPORAL-LOBE EPILEPSY

被引：10

作者：

PAWLIK, G ^{[1
]}

FINK, GR ^{[1
]}

KESSLER, J ^{[1
]}

HEISS, WD ^{[1
]}

机构：

[1] UNIV COLOGNE,HOSP NEUROL,MAX PLANCK INST NEUROL RES,W-5000 COLOGNE,GERMANY

来源：

ACTA NEUROLOGICA SCANDINAVICA | 1994年 / 89卷

关键词：

EPILEPSY; COMPLEX PARTIAL; TEMPORAL LOBE; RADIONUCLIDE IMAGING; ECT RADIOISOTOPES; DEOXYGLUCOSE ANALOGS; COGNITIVE STIMULATION; DOMINANCE CEREBRAL;

D O I：

10.1111/j.1600-0404.1994.tb05210.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Thirty-seven patients with severe temporal lobe epilepsy were studied interictally with [F-18]fluorodeoxyglucose-PET in each of three conditions: resting, during emotional speech, and while performing a visual recognition task. In the resting state, each patient exhibited regional hypometabolism in agreement with his epileptic EEG focus, but that area was typically very large. The zone of maximum dysfunction was significantly better demarcated on activated scans showing an increase in whole-brain metabolism averaging 18%. Concurrently, the midtemporal-focus metabolic contrast was improved by 27%. This effect was more consistently produced by the speech paradigm that also induced significant amygdala recruitment and revealed the individual hemispheric speech dominance. Psychological trait factors played a role only for unspecific global activation.

引用

页码：150 / 156

页数：7