CYTOGENETIC ABNORMALITIES IN THYROID ADENOMAS

被引：27

作者：

ANTONINI, P

VENUAT, AM

LINARES, G

CAILLOU, B

SCHLUMBERGER, M

TRAVAGLI, JP

BERGER, R

PARMENTIER, C

机构：

[1] INST GUSTAVE ROUSSY,DEPT CHIRURG,F-94805 VILLEJUIF,FRANCE

[2] INST GUSTAVE ROUSSY,ANAT PATHOL LAB,F-94805 VILLEJUIF,FRANCE

[3] HOP ST LOUIS,INSERM,U301,F-75010 PARIS,FRANCE

[4] HOP ST LOUIS,CNRS,LOI,F-75010 PARIS,FRANCE

来源：

CANCER GENETICS AND CYTOGENETICS | 1991年 / 52卷 / 02期

关键词：

D O I：

10.1016/0165-4608(91)90458-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic investigations using short-term cultures are reported in six thyroid adenomas. Clonal and nonclonal numerical chromosomal changes were present in two tumors. In two of the four remaining, nonclonal numerical and structural abnormalities were observed, whereas only normal karyotypes were found in the other two. Chromosome 10 and 17 were involved in several cases, although no common clonal changes could be detected. The present studies show that thyroid adenomas, benign tumors of an endocrine gland, may have chromosomal abnormalities, as described for other benign tumors.

引用

页码：157 / 164

页数：8

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