EVALUATION OF ROBOT AUTOMATED DRUG DISSOLUTION MEASUREMENTS

被引：29

作者：

PAPAS, AN ^{[1
]}

ALPERT, MY ^{[1
]}

MARCHESE, SM ^{[1
]}

FITZGERALD, JW ^{[1
]}

机构：

[1] BOSTON UNIV,DEPT CHEM,BOSTON,MA 02215

来源：

ANALYTICAL CHEMISTRY | 1985年 / 57卷 / 07期

关键词：

ROBOTS; INDUSTRIAL; -; Applications;

D O I：

10.1021/ac00284a051

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A controlled study was conducted to evaluate the feasibility of robotic automation of routine regulatory drug dissolution measurements. A commercially available laboratory robot system automated a number of dissolution analyses while concurrent manually acquired samples were analyzed by the same analytical method. The results were subjected to a statistical analysis of variance (ANOVA). After some small sources of systematic bias were eliminated, the results obtained by the robot were statistically indistinguishable from the manual results.

引用

页码：1408 / 1411

页数：4

共 12 条

[1] LONG-TERM CONTROLLED NAVEL ADMINISTRATION OF TESTOSTERONE [J].