HUMAN ALPHA-1-PROTEINASE INHIBITOR - CRYSTAL-STRUCTURE ANALYSIS OF 2 CRYSTAL MODIFICATIONS, MOLECULAR-MODEL AND PRELIMINARY-ANALYSIS OF THE IMPLICATIONS FOR FUNCTION

被引:679
作者
LOEBERMANN, H
TOKUOKA, R
DEISENHOFER, J
HUBER, R
机构
关键词
D O I
10.1016/0022-2836(84)90298-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
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页码:531 / 556
页数:26
相关论文
共 59 条
[1]   ENZYMATIC REDUCTION OF OXIDIZED ALPHA-1-PROTEINASE INHIBITOR RESTORES BIOLOGICAL-ACTIVITY [J].
ABRAMS, WR ;
WEINBAUM, G ;
WEISSBACH, L ;
WEISSBACH, H ;
BROT, N .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (12) :7483-7486
[2]   TRANSLATION AND PROCESSING OF NORMAL (PIMM) AND ABNORMAL (PIZZ) HUMAN ALPHA-1-ANTITRYPSIN [J].
BATHURST, IC ;
STENFLO, J ;
ERRINGTON, DM ;
CARRELL, RW .
FEBS LETTERS, 1983, 153 (02) :270-274
[3]  
BEATTY K, 1980, J BIOL CHEM, V255, P3931
[4]   DO GENES-IN-PIECES IMPLY PROTEINS-IN-PIECES [J].
BLAKE, CCF .
NATURE, 1978, 273 (5660) :267-267
[5]   3-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN PANCREATIC SECRETORY TRYPSIN-INHIBITOR (KAZAL TYPE) AND TRYPSINOGEN AT 1-8 A RESOLUTION - STRUCTURE SOLUTION, CRYSTALLOGRAPHIC REFINEMENT AND PRELIMINARY STRUCTURAL INTERPRETATION [J].
BOLOGNESI, M ;
GATTI, G ;
MENEGATTI, E ;
GUARNERI, M ;
MARQUART, M ;
PAPAMOKOS, E ;
HUBER, R .
JOURNAL OF MOLECULAR BIOLOGY, 1982, 162 (04) :839-868
[6]   OVALBUMIN GENE IS SPLIT IN CHICKEN DNA [J].
BREATHNACH, R ;
MANDEL, JL ;
CHAMBON, P .
NATURE, 1977, 270 (5635) :314-319
[7]   METHODS AND PROGRAMS FOR DIRECT-SPACE EXPLOITATION OF GEOMETRIC REDUNDANCIES [J].
BRICOGNE, G .
ACTA CRYSTALLOGRAPHICA SECTION A, 1976, 32 (SEP1) :832-847
[8]  
BRISCOE WA, 1966, AM REV RESPIR DIS, V94, P529
[9]  
CARLSON J, 1982, J BIOL CHEM, V257
[10]   POTENTIAL MECHANISM OF EMPHYSEMA - ALPHA-1-PROTEINASE INHIBITOR RECOVERED FROM LUNGS OF CIGARETTE SMOKERS CONTAINS OXIDIZED METHIONINE AND HAS DECREASED ELASTASE INHIBITORY CAPACITY [J].
CARP, H ;
MILLER, F ;
HOIDAL, JR ;
JANOFF, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (06) :2041-2045