DOMINANT LETHAL ASSAY IN FEMALE MICE AFTER ORAL DOSING WITH DICHLORVOS OR EXPOSURE TO ATMOSPHERES CONTAINING DICHLORVOS

Female mice were exposed to dichlorvos either through oral doses of 25 and 50 mg/kg body weight or through inhalation of test atmospheres containing 2 and 8 .mu.g dichlorvos/1 air. A 3rd group was injected i.p. with 100 mg/kg body weight with methylmethanesulfonate (MMS). The females were mated with controlled males, and compared for implantation survival. No detrimental effects were observed in the dichlorvos treated groups, while definite reductions were found due to lethal inductions by MMS.