NEUROENDOCRINE DIFFERENTIATION IN MALE BREAST CARCINOMAS

被引：2

作者：

ALM, P ^{[1
]}

ALUMETS, J ^{[1
]}

BAKJENSEN, E ^{[1
]}

OLSSON, H ^{[1
]}

机构：

[1] UNIV LUND HOSP, DEPT ONCOL, S-22185 LUND, SWEDEN

来源：

APMIS | 1992年 / 100卷 / 08期

关键词：

BREAST CARCINOMA; IMMUNOHISTOCHEMISTRY; NEUROENDOCRINE DIFFERENTIATION;

D O I：

10.1111/j.1699-0463.1992.tb03990.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The presence of neuroendocrine differentiation, as expressed by cellular chromogranin immunoreactivity, was investigated in paraffin-embedded tissue material from 51 consecutive cases of male breast carcinoma. From six of these cases electron microscopic studies were included. Chromogranin-immunoreactive cells were present in solid cords and delineated tubular structures. Ultrastructurally, dense core secretory granules could be detected. The expression of neuroendocrine differentiation was 45%, which is between two and eight times higher than reported for female breast carcinomas by other investigators. The present findings suggest that male breast carcinoma is an exclusive tumour disease showing both similarities and discrepancies when compared to its female counterpart.

引用

页码：720 / 726

页数：7

共 25 条

[1]

ABRAHAMSSON PA, 1988, THESIS U LUND LUND

[2] CARCINOID-TUMORS OF THE BREAST - THE MORPHOLOGICAL SPECTRUM OF ARGYROPHIL CARCINOMAS [J].