POTENTIAL SWEETENING AGENTS OF PLANT-ORIGIN .29. STUDIES ON INDONESIAN MEDICINAL-PLANTS .5. SELLIGUEAIN-A, A NOVEL HIGHLY SWEET PROANTHOCYANIDIN FROM THE RHIZOMES OF SELLIGUEA-FEEI

被引：33

作者：

BAEK, NI ^{[1
]}

CHUNG, MS ^{[1
]}

SHAMON, L ^{[1
]}

KARDONO, LBS ^{[1
]}

TSAURI, S ^{[1
]}

PADMAWINATA, K ^{[1
]}

PEZZUTO, JM ^{[1
]}

SOEJARTO, DD ^{[1
]}

KINGHORN, AD ^{[1
]}

机构：

[1] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 09期

关键词：

D O I：

10.1021/np50099a011

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Selligueain A, a novel sweet trimeric proanthocyanidin with a doubly linked A unit, has been isolated from the rhizomes of Selliguea feei collected in Indonesia. The structure of this substance was established as epiafzelechin-(4beta --> 8, 2beta --> O --> 7)-epiafzelechin-(4beta --> 8)-afzelechin [1], on the basis of a combination of spectral and chemical methods. The compound was not acutely toxic for mice and not mutagenic in a forward mutation assay utilizing Salmonella typhimurium strain TM677. Selligueain A [1] was rated by a taste panel as exhibiting about 35 times the sweetness intensity of a 2% w/v aqueous sucrose solution, and at a concentration of 0.5% w/v in H2O was perceived as pleasant-tasting rather than astringent.

引用

页码：1532 / 1538

页数：7

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