ASYMMETRIC-SYNTHESIS OF (S)-VIGABATRIN - AN APPROACH USING METHIONINE AS THE CHIRAL POOL

被引：0

作者：

WEI, ZY ^{[1
]}

KNAUS, EE ^{[1
]}

机构：

[1] UNIV ALBERTA,FAC PHARM & PHARMACEUT SCI,EDMONTON T6G 2N8,ALBERTA,CANADA

来源：

SYNLETT | 1993年 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient methodology for the enantioselective synthesis of (S)-gamma-vinyl GABA was developed. The target chiral compound was prepared starting from commercially available (R)-methionine in five steps in 27% overall yield.

引用

页码：295 / 296

页数：2

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