N-DEMETHYLATION OF MORPHINE IN RAT-BRAIN IS LOCALIZED IN SITES WITH HIGH OPIATE RECEPTOR CONTENT

被引：60
作者：
FISHMAN, J
HAHN, EF
NORTON, BI
机构：
[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT BIOCHIM,BRONX,NY 10461
[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,MONTEFIORE HOSP & MED CTR,INST STEROID RES,BRONX,NY 10461
来源：
NATURE | 1976年 / 261卷 / 5555期
关键词：
D O I：
10.1038/261064a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：64 / 65
页数：2
相关论文
共 25 条
[1]  
ADLER TK, 1967, J PHARMACOL EXP THER, V156, P585
[2]   POSSIBLE MECHANISM OF TOLERANCE TO NARCOTIC DRUGS [J].
AXELROD, J .
SCIENCE, 1956, 124 (3215) :263-264
[3]  
AXELROD J, 1956, J PHARMACOL EXP THER, V117, P322
[4]   ANALGESICS AND THEIR ANTAGONISTS - SOME STERIC AND CHEMICAL CONSIDERATIONS .3. THE INFLUENCE OF THE BASIC GROUP ON THE BIOLOGICAL RESPONSE [J].
BECKETT, AH ;
CASY, AF ;
HARPER, NJ .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1956, 8 (11) :874-883
[5]   CLASTIC BINDING ON OPIATE RECEPTOR [J].
BELLEAU, B ;
MORGAN, P .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (08) :908-909
[6]   N- AND O-DEMETHLATION OF SOME NARCOTIC ANALGESICS BY BRAIN SLICES FROM MALE AND FEMALE LONG-EVANS RATS [J].
ELISON, C ;
ELLIOTT, HW .
BIOCHEMICAL PHARMACOLOGY, 1963, 12 (12) :1363-&
[7]  
FISHMAN J, 1975, FED PROC, V34, P815
[8]   PREPARATION OF MORPHINE-6-H-3 AND ITS ISOTOPIC STABILITY IN MAN AND IN RAT [J].
FISHMAN, J ;
NORTON, B ;
COTTER, ML ;
HAHN, EF .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (07) :778-781
[9]   REGIONAL STUDIES OF CATECHOLAMINES IN RAT BRAIN .I. DISPOSITION OF [3H]NOREPINEPHRINE [3H]DOPAMINE AND [3H]DOPA IN VARIOUS REGIONS OF BRAIN [J].
GLOWINSKI, J ;
IVERSEN, LL .
JOURNAL OF NEUROCHEMISTRY, 1966, 13 (08) :655-+
[10]  
Herz A., 1971, ADV DRUG RES, V6, P79
123