A Review on Bi-layer Tablets

被引：0

作者：

Namrata, M. ^{[1
]}

Sirisha, V. N. L. ^{[1
]}

Sruthi, B. ^{[1
]}

Harika, I. Bhavani ^{[1
]}

Kirankumar, P. ^{[1
]}

Rao, Y. Kiran Kumar ^{[1
]}

Pranavi, K. ^{[1
]}

Sindhura, S. ^{[1
]}

Krishna, N. Vamsi ^{[1
]}

Rao, O. UmaMaheshwara ^{[1
]}

机构：

[1] JNTUH, Anurag Pharm Coll, Kodad, Andhra Pradesh, India

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH | 2013年 / 2卷 / 04期

关键词：

Geometric configurations; Bilayer tablet; Combination drugs; Incompatible;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The fact that drug delivery systems with altered geometric configurations (particularly tablets) have shown promising results in drug delivery technology and ease of manufacturing is an added advantage to the pharmaceutical industry. It has been elucidated that geometrically altered drug delivery systems, especially bilayered tablets, have provided various advantages to drug delivery technology. The ease of manufacture of these systems adds further benefit in terms of cost. Several pharmaceutical companies are currently developing bi-layer tablets for a variety of reasons: patent extension, therapeutic, marketing, to reduce capital investment, etc. Bi-layer tablets have been developed to achieve controlled delivery of different drugs with pre-defined release profiles. In the last decade, interest in developing a combination of two or more Active Pharmaceutical Ingredients (API) in a single dosage form (bilayer tablet) has increased in the pharmaceutical industry, promoting patient convenience and compliance. Bi-layer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one layer is immediate release as initial dose and second layer is maintenance dose. The present review summarises various aspects of Bilayer tablets.

引用

页码：240 / 246

页数：7

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