Future of bioartificial liver support

被引:22
作者
Chamuleau, Robert A. F. M. [1 ]
机构
[1] Univ Amsterdam, Dept Hepatol, Acad Med Ctr, S Bldg,Floor 1,Room 166,Meibergdreef 69-71, NL-1105 BK Amsterdam, Netherlands
来源
WORLD JOURNAL OF GASTROINTESTINAL SURGERY | 2009年 / 1卷 / 01期
关键词
Acute liver failure; Bioartificial liver; Liver transplantation; Cell transplantation; Tissue engineering; Xenotransplantation;
D O I
10.4240/wjgs.v1.i1.21
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Many different artificial liver support systems (biological and non-biological) have been developed, tested pre-clinically and some have been applied in clinical trials. Based on theoretical considerations a biological artificial liver (BAL) should be preferred above the non-biological ones. However, clinical application of the BAL is still experimental. Here we try to analyze which hurdles have to be taken before the BAL will become standard equipment in the intensive care unit for patients with acute liver failure or acute deterioration of chronic liver disease. (C) 2009 Baishideng. All rights reserved.
引用
收藏
页码:21 / 25
页数:5
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