Chemical constituents and biological studies of Origanum vulgare Linn

被引:31
作者
Rao, Gottumukkala Venkateswara [1 ]
Mukhopadhyay, T. [1 ]
Annamalai, T. [1 ]
Radhakrishnan, N. [1 ]
Sahoo, M. R. [1 ]
机构
[1] CavinKare Res Ctr, 12,Poonamalle Rd,Ekkattuthangal, Madras 600032, Tamil Nadu, India
来源
PHARMACOGNOSY RESEARCH | 2011年 / 3卷 / 02期
关键词
Origanum vulgare Linn; origanol A and B; triterpene acids; tyrosinase inhibition; beta-sitosterol;
D O I
10.4103/0974-8490.81964
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Bioassay-guided isolation of methanolic extract of the leaves of Origanum vulgare Linn., yielded two protocatechuic acid ester derivatives, origanol A (1) and origanol B (2) along with ursolic acid (3), oleanolic acid (4), beta-sitosterol (5), and triacontanol (6). Structures of the compound were established based on physical and spectral data (UV, IR, H-1 and C-13 NMR and mass). Origanol A (1) showed significant mushroom tyrosinase inhibition activity.
引用
收藏
页码:143 / 145
页数:3
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