STEROIDAL SAPONINS FROM THE BULBS OF LILIUM-REGALE AND L-HENRYI

被引：40
|
作者：
MIMAKI, Y
SASHIDA, Y
NAKAMURA, O
NIKAIDO, T
OHMOTO, T
机构：
[1] TOKYO COLL PHARM,1432-1 HORINOUCHI,HACHIOJI,TOKYO 19203,JAPAN
[2] TOHO UNIV,SCH PHARMACEUT SCI,FUNABASHI,CHIBA 274,JAPAN
来源：
PHYTOCHEMISTRY | 1993年 / 33卷 / 03期
关键词：
LILIUM-REGALE; L-HENRYI; LILIACEAE; BULBS; STEROIDAL SAPONINS; 3-HYDROXY-3-METHYLGLUTARIC ACID; CYCLIC AMP PHOSPHODIESTERASE; INHIBITORY ACTIVITY;
D O I：
10.1016/0031-9422(93)85472-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new and three known steroidal saponins were isolated from the fresh bulbs of Lilium regale and two known saponins from those of L. henryi. The structures of the new saponins were established by extensive spectral data, hydrolysis and chemical correlation as (25R)-27-O-[(S)-3-hydroxy-3-methylglutaroyl]-spirost-5-ene-3beta,27-diol 3-O-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranoside and (25S)-spirost-5-ene-3beta,17alpha,27-triol 3-O-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->2)-O-beta-D-glucopyranosyl-(1-->4)]-beta-D-glucopyranoside. Inhibitory activity of the saponins on cyclic AMP phosphodiesterase was evaluated.
引用
收藏
页码：675 / 682
页数：8
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