POTENTIAL ANTITUMOR AGENTS .44. SYNTHESIS AND ANTITUMOR-ACTIVITY OF NEW CLASSES OF DIACRIDINES - IMPORTANCE OF LINKER CHAIN RIGIDITY FOR DNA-BINDING KINETICS AND BIOLOGICAL-ACTIVITY

被引：112

作者：

DENNY, WA ^{[1
]}

ATWELL, GJ ^{[1
]}

BAGULEY, BC ^{[1
]}

WAKELIN, LPG ^{[1
]}

机构：

[1] CANC INST,EXPTL CHEMOTHERAPY UNIT,MELBOURNE,VIC 3000,AUSTRALIA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 11期

关键词：

D O I：

10.1021/jm00149a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1568 / 1574

页数：7

共 37 条

[1]

ADAMS A, 1985, MOL PHARMACOL, V27, P480

[2]

ASSAMUNT A, 1985, BIOCHEMISTRY, V24, P1449

[3]

ATWELL GJ, 1984, SYNTHESIS-STUTTGART, P1032

[4]

ATWELL GJ, J MED CHEM

[5] POTENTIAL ANTI-TUMOR AGENTS .35. QUANTITATIVE RELATIONSHIPS BETWEEN ANTI-TUMOR (L1210) POTENCY AND DNA-BINDING FOR 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE ANALOGS [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) :520-525

[6] DNA-BINDING AND GROWTH INHIBITORY PROPERTIES OF A SERIES OF 2,7-DI-ALKYL-SUBSTITUTED DERIVATIVES OF PROFLAVINE [J].

BAGULEY, BC ;

FERGUSON, LR ;

DENNY, WA .

CHEMICO-BIOLOGICAL INTERACTIONS, 1982, 42 (01) :97-105

[7] ANTI-TUMOR ACTIVITY OF SUBSTITUTED 9-ANILINOACRIDINES - COMPARISON OF INVIVO AND INVITRO TESTING SYSTEMS [J].

BAGULEY, BC ;

NASH, R .

EUROPEAN JOURNAL OF CANCER, 1981, 17 (06) :671-679

[8] POTENTIAL ANTI-TUMOR AGENTS .34. QUANTITATIVE RELATIONSHIPS BETWEEN DNA-BINDING AND MOLECULAR-STRUCTURE FOR 9-ANILINOACRIDINES SUBSTITUTED IN THE ANILINO RING [J].

BAGULEY, BC ;

DENNY, WA ;

ATWELL, GJ ;

CAIN, BF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (02) :170-177

[9] FORMULATION AND STABILITY OF THE ANTI-NEOPLASTIC AGENT - N,N'-DI-9-ACRIDINYL-1,6-HEXANEDIAMINE (NSC =219733) [J].

BELTAGY, YA ;

WAUGH, W ;

REPTA, AJ .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1980, 6 (04) :411-421

[10]

CANELLAKIS ES, 1976, BIOCH BIOPHYS ACTA, V418, P289

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