Current status of stem cells in cardiac repair

被引：9
作者：
Henning, Robert J. [1 ,2 ]
机构：
[1] Univ S Florida, Coll Publ Hlth, Dept Environm & Occupat Hlth, Tampa, FL 33612 USA
[2] James A Haley Hosp, Tampa, FL 33612 USA
来源：
FUTURE CARDIOLOGY | 2018年 / 14卷 / 02期
关键词：
acute myocardial infarction; anti-inflammatory cytokines; cardiomyopathy; cardiopoietic mesenchymal stem cells; cardiosphere-derived cells; c-kit cardiac stem/progenitor cells; congestive heart failure; embryonic stem cells; exosomes; growth factors; mesenchymal stem cells; paracrine factors; Pim-1;
D O I：
10.2217/fca-2017-0072
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
One out of every two men and one out of every three women greater than the age of 40 will experience an acute myocardial infarction (AMI) at some time during their lifetime. As more patients survive their AMIs, the incidence of congestive heart failure (CHF) is increasing. 6 million people in the USA have ischemic cardiomyopathies and CHF. The search for new and innovative treatments for patients with AMI and CHF has led to investigations and use of human embryonic stem cells, cardiac stem/progenitor cells, bone marrow-derived mononuclear cells and mesenchymal stem cells for treatment of these heart conditions. This paper reviews current investigations with human embryonic, cardiac, bone marrow and mesenchymal stem cells, and also stem cell paracrine factors and exosomes.
引用
收藏
页码：181 / 192
页数：12
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