PENICILLIN CONCENTRATIONS AFTER INCREASED DOSES OF BENZATHINE PENICILLIN-G FOR PREVENTION OF SECONDARY RHEUMATIC-FEVER

被引：27

作者：

CURRIE, BJ

BURT, T

KAPLAN, EL

机构：

[1] MENZIES SCH HLTH RES,DARWIN,NT 0811,AUSTRALIA

[2] UNIV MINNESOTA,SCH MED,DEPT PEDIAT,MINNEAPOLIS,MN 55455

[3] UNIV MINNESOTA,SCH MED,WHO,COLLABORATING CTR REFERENCE & RES STREPTOCOCCI,MINNEAPOLIS,MN 55455

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 05期

关键词：

D O I：

10.1128/AAC.38.5.1203

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Plasma penicillin levels were studied 2, 3, and 4 weeks after intramuscular benzathine penicillin G (BPG) doses of 1,200,000, 1,800,000, and 2,400,000 U. Proportions of patients with penicillin levels above 25 ng/ml at each week increased with increasing BPG dose. Further studies of higher-dose BPG for rheumatic fever prophylaxis are required.

引用

页码：1203 / 1204

页数：2

共 9 条

[1] THE ROLE OF THE STREPTOCOCCUS IN THE PATHOGENESIS OF RHEUMATIC FEVER [J].