DETECTION OF HUMAN PAPILLOMAVIRUS TYPES 16 AND 18 IN THE EXFOLIATED CERVICAL CELLS USING THE POLYMERASE CHAIN-REACTION

被引：5

作者：

NAKAZAWA, A

INOUE, M

SAITO, J

SASAGAWA, T

UEDA, G

TANIZAWA, O

机构：

[1] Department of Obstetrics and Gynecology, Osaka University Medical School, Osaka

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1992年 / 37卷 / 01期

关键词：

HUMAN PAPILLOMAVIRUS; EXFOLIATED CERVICAL CELLS; SQUAMOUS CELL CARCINOMA; SUBCLINICAL HPV INFECTION; POLYMERASE CHAIN REACTION;

D O I：

10.1016/0020-7292(92)90972-L

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We applied the polymerase chain reaction (PCR) to detect HPV 16 and 18 in cytological samples obtained from the uterine cervices of Japanese women. HPV infection was detected in 17 (25%) of 67 with CIN and 11 (37%) of 30 with cervical carcinoma. It is notable that 11 (16%) of 69 women with normal cervices were infected with either HPV 16 or 18. The polymerase chain reaction is sensitive and useful for epidemiological studies.

引用

页码：13 / 18

页数：6

共 26 条

[1] THE E6-E7 REGION OF HUMAN PAPILLOMAVIRUS TYPE-18 IS SUFFICIENT FOR TRANSFORMATION OF NIH-3T3 AND RAT-1 CELLS [J].