STUDIES ON THE CHEMISTRY OF O,N-CONTAINING AND S,N-CONTAINING HETEROCYCLES .12. INVESTIGATIONS ON THE SYNTHESIS OF TRICYCLIC 1,5-BENZOXAZEPINES

被引：18

作者：

BARTSCH, H

ERKER, T

机构：

[1] Institute of Pharmaceutical Chemistry, University of Vienna, Vienna, A-1090

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 04期

关键词：

D O I：

10.1002/jhet.5570270432

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of methylthiolactim 1 with weak basic N‐nucleophiles led to the substituted benzoxazepines 2,3 and 6a‐d, respectively. Compound 4 was obtained by condensation of 3 with carbonyldiimidazole, whereas 6a‐d were transformed thermically into the triazolobenzoxazepines 7a‐d. Treatment of 6b with thionyl chloride afforded 8. Compound 9 directly was obtained from 1 with anthranilic acid. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：991 / 993

页数：3