A CASE OF NEUROFIBROMATOSIS TYPE 1

被引：0

作者：

Dimitrova, Valentina ^{[1
]}

Yordanova, Ivelina ^{[1
]}

Pavlova, Verka ^{[1
]}

Valtchev, Valentin ^{[1
]}

Gospodinov, Dimitar ^{[1
]}

Parashkevova, Boryana ^{[2
]}

Balabanov, Chavdar ^{[2
]}

机构：

[1] Med Univ Pleven, Dept Dermatol & Venereol, 91 Gen Vladimir Vazov Str, Pleven 5800, Bulgaria

[2] Med Univ Pleven, Dept Ophthalmol, Pleven, Bulgaria

来源：

JOURNAL OF IMAB | 2008年 / 14卷 / 01期

关键词：

Neurofibromatosis; Neurofibromatosis type I; Recklinghausen's disease;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neurofibromatosis (NF) is a term that has been applied to a variety of related syndromes, characterized by neuroectodermal tumors arising within multiple organs and autosomal-dominant inheritance. Neurofibromatosis type I (NF-1), known as well as Recklinghausen's disease, is the most common type of the disease accounting 90% of the cases. We present a case of 52-year-old men with NF-1. The disease started in childhood with the appearance of multiple hyperpigmented skin macules. At the age of 46 a lot of cutaneous tumors appeared and started growing bigger all over the body surface. Because of a vision problem due to an upper left eyelid neurofibroma, the patient came for a clinical examination at the age of 52 years.

引用

页码：63 / 67

页数：5

共 15 条

[1] Growth rate characteristics of acoustic neuromas associated with neurofibromatosis type 2 [J].

Abaza, MM ;

Makariou, E ;

Armstrong, M ;

Lalwani, AK .

LARYNGOSCOPE, 1996, 106 (06) :694-699

[2] AXILLARY FRECKLING AS DIAGNOSTIC AID IN NEUROFIBROMATOSIS [J].

CROWE, FW .

ANNALS OF INTERNAL MEDICINE, 1964, 61 (06) :1142-+

[3]

Crowe FW SW, 1956, CLIN PATHOLOGICAL GE

[4] VONRECKLINGHAUSEN NEUROFIBROMATOSIS - A CLINICAL AND POPULATION STUDY IN SOUTHEAST WALES [J].

HUSON, SM ;

HARPER, PS ;

COMPSTON, DAS .

BRAIN, 1988, 111 :1355-1381

[5] OCULAR AND ORBITAL MANIFESTATIONS OF NEUROFIBROMATOSIS [J].

KOBRIN, JL ;

BLODI, FC ;

WEINGEIST, TA .

SURVEY OF OPHTHALMOLOGY, 1979, 24 (01) :45-51

[6]

LEWIS RA, 1981, OPHTHALMOLOGY, V88, P348

[7] LISCH NODULES IN NEUROFIBROMATOSIS TYPE-1 [J].

LUBS, MLE ;

BAUER, MS ;

FORMAS, ME ;

DJOKIC, B .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (18) :1264-1266

[8]

RICCARDI V M, 1982, Current Problems in Cancer, V7, P1, DOI 10.1016/S0147-0272(82)80016-0

[9]

Riccardi VM., 1986, NEUROFIBROMATOSIS PH

[10]

SKUSE GR, 1991, AM J HUM GENET, V49, P600

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