THE THIAZOLIUM CATALYZED BENZOIN CONDENSATION WITH MILD BASE DOES NOT INVOLVE A DIMER INTERMEDIATE

被引：80

作者：

BRESLOW, R

KIM, R

机构：

[1] Department of Chemistry, Columbia University New York

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75794-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic studies show that the benzoin condensation catalyzed by 3,4,5-trimethylthiazolium iodide and triethylamine in DMSO has a transition state with two benzaldehyde and one thiazolium;components, while the conversion of nitrobenzaldehyde to the thiazolium adduct is kinetically first order in thiazolium salt and aldehyde. These findings exclude proposals that thiazolium dimers are the true catalytic species.

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页码：699 / 702

页数：4

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