CORRELATION OF MEAN PLATELET VOLUME AND PLATELET DISTRIBUTION WIDTH IN RISK CATEGORIES OF DENGUE FEVER- A PILOT STUDY

BACKGROUND Incidence of dengue fever is on rise in India. We investigated the characteristics of Mean Platelet Volume (MPV) and platelet distribution width (PDW) in various risk categories of dengue fever. MATERIALS AND METHODS In this prospective two months pilot study, 100 cases of NS1 antigen and IgM ELISA positive dengue were included. Platelet count for risk categorisation, MPV and PDW values were recorded. Statistical analysis was done using ANOVA (Fisher's test). RESULTS There were 77%, 18% and 5% cases in no, low and moderate risk categories, respectively. In no, low and moderate risk categories, mean MPV was 8.6, 9.6 and 10.7 (fL), respectively. In no, low and moderate risk categories mean PDW was 16.4, 17.03 and 16.9, respectively. Overall, there was positive correlation between MPV and PDW (p= 0.066; r= 0.185), as also in low risk category. In moderate risk group, there was a negative correlation between MPV and PDW (p= 0.201; r= -0.686). CONCLUSION Hence, a positive correlation was seen between MPV and PDW in low risk group, but no correlation was seen in no risk group.