AN ANTIMICROBIAL ALKALOID FROM FICUS-SEPTICA

被引：111

作者：

BAUMGARTNER, B ^{[1
]}

ERDELMEIER, CAJ ^{[1
]}

WRIGHT, AD ^{[1
]}

RALI, T ^{[1
]}

STICHER, O ^{[1
]}

机构：

[1] UNIV PAPUA NEW GUINEA,DEPT CHEM,PORT MORESBY,PAPUA N GUINEA

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 10期

关键词：

antimicrobial activity; Ficus septica; indolizidine alkaloids; leaves; Moraceae;

D O I：

10.1016/0031-9422(90)80209-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A methanolic extract ofFicus septica leaves displayed intense antibacterial and antifungal activities. Bioactivity-guided fractionation with TLC bioautography led to the isolation of two indolizidine alkaloids, the novel ficuseptine, 4,6-bis-(4-methoxyphenyl)- 1,2,3-trihydroindolizidinium chloride, and antofine. The structure of ficuseptine was determined from mass spectrometry and extensive one and two dimensional NMR spectroscopy. Complete1H and13C NMR assignments for antofine are reported. © 1990 Pergamon Press plc.

引用

页码：3327 / 3330

页数：4

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