T-CELL ACTIVATION - 2-FOR-T

被引：38

作者：

GUERDER, S ^{[1
]}

FLAVELL, RA ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,HOWARD HUGHES MED INST,NEW HAVEN,CT 06520

来源：

CURRENT BIOLOGY | 1995年 / 5卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0960-9822(95)00175-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

T-cell activation requires costimulation in addition to the antigen-specific signal. Recent results suggest that distinct costimulatory molecules can specifically activate different types of T-cell response.

引用

页码：866 / 868

页数：3

共 22 条

[1] BLOCKADE OF THE CD28 COSTIMULATORY PATHWAY - A MEANS TO INDUCE TOLERANCE [J].

BOUSSIOTIS, VA ;

GRIBBEN, JG ;

FREEMAN, GJ ;

NADLER, LM .

CURRENT OPINION IN IMMUNOLOGY, 1994, 6 (05) :797-807

[2] TARGETING AUTOANTIGEN TO B-CELLS PREVENTS THE INDUCTION OF A CELL-MEDIATED AUTOIMMUNE-DISEASE IN RATS [J].

DAY, MJ ;

TSE, AGD ;

PUKLAVEC, M ;

SIMMONDS, SJ ;

MASON, DW .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (03) :655-659

[3] ABSENCE OF B7-DEPENDENT RESPONSES IN CD28-DEFICIENT MICE [J].

GREEN, JM ;

NOEL, PJ ;

SPERLING, AI ;

WALUNAS, TL ;

GRAY, GS ;

BLUESTONE, JA ;

THOMPSON, CB .

IMMUNITY, 1994, 1 (06) :501-508

[4] CTLA4 MEDIATES ANTIGEN-SPECIFIC APOPTOSIS OF HUMAN T-CELLS [J].

GRIBBEN, JG ;

FREEMAN, GJ ;

BOUSSIOTIS, VA ;

RENNERT, P ;

JELLIS, CL ;

GREENFIELD, E ;

BARBER, M ;

RESTIVO, VA ;

KE, XY ;

GRAY, GS ;

NADLER, LM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (03) :811-815

[5] CD28-MEDIATED SIGNALING CO-STIMULATES MURINE T-CELLS AND PREVENTS INDUCTION OF ANERGY IN T-CELL CLONES [J].

HARDING, FA ;

MCARTHUR, JG ;

GROSS, JA ;

RAULET, DH ;

ALLISON, JP .

NATURE, 1992, 356 (6370) :607-609

[6] THE TISSUE DISTRIBUTION OF THE B7-2 COSTIMULATOR IN MICE - ABUNDANT EXPRESSION ON DENDRITIC CELLS IN-SITU AND DURING MATURATION IN-VITRO [J].

INABA, K ;

WITMERPACK, M ;

INABA, M ;

HATHCOCK, KS ;

SAKUTA, H ;

AZUMA, M ;

YAGITA, H ;

OKUMURA, K ;

LINSLEY, PS ;

IKEHARA, S ;

MURAMATSU, S ;

HODES, RJ ;

STEINMAN, RM .

JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (05) :1849-1860

[7] THE B7 AND CD28 RECEPTOR FAMILIES [J].

JUNE, CH ;

BLUESTONE, JA ;

NADLER, LM ;

THOMPSON, CB .

IMMUNOLOGY TODAY, 1994, 15 (07) :321-331

[8] B7-1 AND B7-2 COSTIMULATORY MOLECULES ACTIVATE DIFFERENTIALLY THE TH1/TH2 DEVELOPMENTAL PATHWAYS - APPLICATION TO AUTOIMMUNE-DISEASE THERAPY [J].

KUCHROO, VK ;

DAS, MP ;

BROWN, JA ;

RANGER, AM ;

ZAMVIL, SS ;

SOBEL, RA ;

WEINER, HL ;

NABAVI, N ;

GLIMCHER, LH .

CELL, 1995, 80 (05) :707-718

[9] HIGH-INCIDENCE OF SPONTANEOUS AUTOIMMUNE ENCEPHALOMYELITIS IN IMMUNODEFICIENT ANTIMYELIN BASIC-PROTEIN T-CELL RECEPTOR TRANSGENIC MICE [J].

LAFAILLE, JJ ;

NAGASHIMA, K ;

KATSUKI, M ;

TONEGAWA, S .

CELL, 1994, 78 (03) :399-408

[10]

LAFFERTY KJ, 1993, ANNU REV IMMUNOL, V1, P143

← 1 2 3 →