Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease

被引：7

作者：

Leo, Fabian ^{[1
]}

Zeh, Michael ^{[2
]}

Prothmann, Annegret ^{[3
]}

Kurzai, Oliver ^{[4
,5
]}

Kurz, Sylke ^{[1
]}

Grohe, Christian ^{[1
]}

机构：

[1] Evangel Lungenklin Berlin, Dept Resp Med, Lindenberger Weg 27, D-13125 Berlin, Germany

[2] Inst Pathol, Biopt Inst, Lindenberger Weg 27, D-13125 Berlin, Germany

[3] Evangel Lungenklin Berlin, Dept Radiol, Lindenberger Weg 27, D-13125 Berlin, Germany

[4] German Natl Reference Ctr Invas Fungal Infect NRZ, Leibniz Inst Nat Prod Res & Infect Biol, Adolf Reichwein Str 23, D-07745 Jena, Germany

[5] Univ Wurzburg, Inst Hyg & Microbiol, Josef Schneider Str 2-E1, D-97080 Wurzburg, Germany

来源：

MEDICAL MYCOLOGY CASE REPORTS | 2018年 / 20卷

关键词：

Tracheal mucormycosis; Pulmonary mucormycosis; Lichtheimia; Organizing pneumonia;

D O I：

10.1016/j.mmcr.2018.02.001

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome. Mucormycosis was confirmed by histopathology from tracheal specimens and molecular evidence of Lichtheimia. A surgical approach was not possible because of the multifocal disease pattern and the extent of tracheal involvement. The patient was successfully treated with liposomal amphotericin B followed by posaconazole maintenance therapy. After 9 months, recurrent pulmonary mucormycosis was suspected but emerged as organizing pneumonia without evidence of active fungal infection.

引用

页码：28 / 32

页数：5

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